問題詳情

請依下文回答第 18 題至第 20 題 In 1988, a college dropout named Jonathan Stanley was convinced that government agents were chasing afterhim. For three days and nights he raced through streets and subway tunnels. After the police took him to a hospital, hefinally received effective treatment two years after getting a diagnosis of bipolar disorder. “My son’s life was saved,”his father, Ted Stanley, said. He then created a foundation to support psychiatric research. In July 2014, the StanleyFamily Foundation donated $650 million to Broad Institute of MIT and Harvard, a research center to which he hadearlier donated $100 million. It comes at a time when research into mental illness is sputtering. The Broad Institutetimed its announcement of the donation to coincide with the release of the largest analysis ever on the genetics ofschizophrenia. The analysis identified more than 100 regions of DNA associated with the disease. Many contain genesinvolved in just a few biological functions, like pumping calcium into neurons that could help guide the search fortreatments. “For the first time, there’s a clear path forward,” said Eric Lander of the Broad Institute. When scientistsdiscovered psychiatric drugs like lithium in the mid-20th century, they did so mostly by accident. For years, theyhoped figuring out the action of the drugs would help them understand the causes of the diseases. But they came upempty. Some researchers argued that a better strategy would be to find the genes involved in psychiatric disorders.This approach would give them new molecular targets for drugs they could test. Recent research has found thatmutations in the very same gene can cause a wide range of brain disorders, including autism, schizophrenia, andepilepsy. “We have no idea at all about why that is, and the only way to find out is to do some hard biology – to findout not only which genes matter, but what about them matters,” Dr. Goldstein said. The new study found that manyrisk variants clustered around specific body functions, like the immune system and calcium transmission in brain cells.To understand their underlying biology, Broad researchers plan to grow neurons with mutations in the genes they havefound, to see how they differ from normal cells. They will engineer mutated mice to see how their brains are affected.These studies will be expensive, which is where the Stanley Family Foundation comes in.
18 According to the passage, why did Mr. Ted Stanley want to support psychiatric research?
(A) His son received effective treatment and recovered.
(B) He feared that he would have psychiatric disorder.
(C) His son had a nonfunctioning brain for the rest of his life.
(D) He feared that there was a government conspiracy involved.

參考答案

答案：A
難度：適中0.608247
統計：A(59),B(9),C(17),D(10),E(0)

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