91Which one of the following is true regarding seizures as one of the multiple side effects fromthe use of opioids?
(A) Morphine and related opioids can cause seizure activity when moderate doses are given.
(B) Seizure activity is more likely with meperidine, especially in the elderly and with renal dysfunction.
(C) Seizure activity is mediated through stimulation of N-methyl-D-aspartate (NMDA) receptors.
(D) Naloxone is very effective in treating seizures produced by morphine and related drugs includingmeperidine.
(E) Seizure activity is most likely related to the fact that opioids stimulate the production of γ-aminobutyricacid (GABA).