2.許多惡性腫瘤常有致癌基因(oncogene)的改變或活化。以下各種致癌基因的改變與癌症的配對，哪些是正確的? (1)BRAF point mutation與melanoma (2)CTNNB1 point mutation與prostate cancer (3)FOS overexpression與osteosarcomas (4)ERBB2 amplification或point mutation與colon cancer (5)N-MYC amplification與neuroblastoma
(A)(1)+(2)+(3)+(4)
(B)(2)+(3)+(4)+(5)
(C)(1)+(2)+(4)+(5)
(D)(1)+(2)+(3)+(5)
(E)(1)+(2)+(3)+(4)+(5)