5. Both water and glucose share an–OH that can serve as a substrate for a reaction with the terminal phosphate ofATP catalyzed by hexokinase. Glucose, however, is about a million times more reactive as a substrate than water.The best explanation is that: 
(A) the larger glucose binds better to the enzyme; it induces a conformational change in hexokinase that bringsactive-site amino acids into position for catalysis.
(B) glucose has more –OH groups per molecule than does water.
(C) the–OH group of water is attached to an inhibitory H atom, while the glucose –OH group is attached to C.
(D) water and the second substrate, ATP, compete for the active site resulting in a competitive inhibition of theenzyme.
(E) water normally will not reach the active site because it is hydrophobic.