問題詳情

16-20Applying a new genomic technique to a large group of patients, researchers in Britainhave detected DNA variations that underlie seven common diseases, discovering unexpectedlinks between them. The variations pinpoint biological pathways underlying each of thediseases, and researchers hope that 16 , new drugs and treatments will emerge. Theseven common diseases are bipolar disorder, coronary artery disease, Crohn’s disease,hypertension, rheumatoid arthritis, and Type 1 and Type 2 diabetes.Unveiling the complex genetics of common diseases was the promised payoff of the$3 billion human genome project, completed in 2003, but 17 until the recentdevelopment of devices that in a single operation can read the DNA sequence at up to500,000 points across an individual’s genome. And 18 , called chips, researchers cancompare large numbers of patients with healthy individuals, looking for points of differencesin their genomes that 19 .The approach is known as whole genome association, and studies on Type 2 diabetes,heart disease and breast cancer have been reported within the last few weeks. Those and thenew study, 20 , demonstrate the power and reliability of the whole genome associationmethod, which stands in contrast to the many uncorroborated claims of disease genes madepreviously.
(A) with the devices
(B) progress was slow
(C) which was financed by the Wellcome Trust of London
(D) may be associated with disease
(E) as the pathways are analyzed
16

參考答案

答案：E
難度：適中0.636364
統計：A(0),B(1),C(0),D(3),E(7)

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